Myopia is a widespread visual issue that warrants immediate attention, especially in Asia [ 1 , 2 ]. However, the definitive mechanism of myopia remains unclear, making intervention strategies elusive [ 3 ]. As of today, no existing method has …
The development of treatments targeting the vascular endothelial growth factor (VEGF) signaling pathways have traditionally been firstly investigated in oncology and then advanced into retinal disease indications. Members of the VEGF family of …
verfasst von:
Ian M. Leitch, Michael Gerometta, David Eichenbaum, Robert P. Finger, Nathan C. Steinle, Megan E. Baldwin
Pituitary adenomas (PA), common benign tumors in the sellar region, often impair vision and visual field [ 1 ]. Transsphenoidal surgery, a prevalent and safe method, aims to decompress the optic chiasm and enhance vision, but predicting visual …
Age-related macular degeneration (AMD) is a significant cause of blindness affecting > 6 million individuals globally [ 1 , 2 ]. Compelling evidence points to the crucial role of impaired choroidal flow signal in the development of AMD. Recent …
verfasst von:
Max Brinkmann, Pasquale Viggiano, Giacomo Boscia, Tom Müller, Niccolò Castellino, Jakob Schweighofer, Francesco Boscia, Mario Damiano Toro, Yosuf El-Shabrawi
Cytomegalovirus (CMV), a herpesvirus, is prevalent globally, with an estimated CMV immunoglobulin G (IgG) seroprevalence of 66–90% [ 1 ]. CMV persists in latent form following initial infection in humans and reactivates episodically to replicate …
verfasst von:
Yunxiao Zang, Yaning Zhao, Rongmei Peng, Gege Xiao, Xiaozhen Liu, Yi Qu, Xuanjun Zhang, Jiaxin Zhang, Jing Hong
Diabetic retinopathy is among the leading causes of blindness (5.6%) and moderate–severe vision impairment (3.0%) worldwide [ 1 ]. Diabetic macular oedema (DMO) is a complication of diabetic retinopathy whereby a failure of the blood–retinal …
verfasst von:
José M. Ruiz-Moreno, María Gámez Lechuga, Pilar Calvo, María Merino, Teresa Martín Lorenzo, Paulina Maravilla-Herrera, Beatriz Gil Jiménez, Maximino J. Abraldes
Age-related macular degeneration (AMD) is a chronic, neurodegenerative, progressive disease that can lead to blindness if left untreated [ 1 ]. More specifically, this disease affects the neural tissue of the retina, and is characterized by the …
verfasst von:
Maximino J. Abraldes, Pilar Calvo, María Gámez Lechuga, María Merino, Teresa Martín Lorenzo, Paulina Maravilla-Herrera, Beatriz Gil Jiménez, José M. Ruiz-Moreno
Aphakia, resulting from the removal of displaced natural or artificial lens, occurring after complicated cataract surgery, trauma, intracapsular cataract removal, or lensectomy (performed because of congenital cataract), is an indication for a …
The travoprost intracameral implant was recently approved by the US Food and Drug Administration for sustained release medical treatment of open-angle glaucoma in the USA. The approval represents a substantial and progressive step forward in the …
Central serous chorioretinopathy (CSCR) is an ocular condition characterized by serous detachment of the retinal pigment epithelium (RPE) and venous congestion of choroidal outflow and fluid buildup/leakage. Visual disturbances include blurred …
An ongoing global shortage of verteporfin (Visudyne®) limits the treatment possibilities for several chorioretinal diseases, including central serous chorioretinopathy, choroidal hemangioma, and polypoidal choroidal vasculopathy. Verteporfin is …
verfasst von:
Marc J. Sirks, Yousif Subhi, Noa Rosenberg, Carla E. M. Hollak, Camiel J. F. Boon, Roselie M. H. Diederen, Suzanne Yzer, Jeannette Ossewaarde-van Norel, Yvonne de Jong-Hesse, Reinier O. Schlingemann, Rob J. Moss, Elon H. C. van Dijk
Penetrating keratoplasty (PKP) stands as a cornerstone in the treatment of various corneal diseases and has undergone significant evolution over the years [ 1 ]. The integration of femtosecond laser-assisted penetrating keratoplasty (Fs-PKP) marks …
verfasst von:
Junxin Ma, Xueqian Cao, Yang Liu, Jin Huang, Yuting Gong, Xinyu Pan, Zhongguo Li, Linnong Wang
Myopia has witnessed a significant global increase in prevalence among children and adolescents [ 1 , 2 ]. Extensive evidence has confirmed that myopic eyes change from generally oblate or spherical shape to a prolate ellipsoid [ 3 – 6 ]. In this …
Sir Nicolas Harold Lloyd Ridley was the first person to successfully implant an intraocular lens (IOL) on November 29, 1949, at St Thomas’ Hospital in London. However, the patient obtained refractive error of − 18.0 D sphere and − 6.0 D cylinder [ …
verfasst von:
Wiktor Stopyra, Oleksiy Voytsekhivskyy, Andrzej Grzybowski
The integration of artificial intelligence (AI) in ophthalmology has promoted the development of the discipline, offering opportunities for enhancing diagnostic accuracy, patient care, and treatment outcomes. This paper aims to provide a …
verfasst von:
Daohuan Kang, Hongkang Wu, Lu Yuan, Yu Shi, Kai Jin, Andrzej Grzybowski
Astigmatism is a prevalent refractive error characterized by an uneven curvature of the cornea or lens, leading to distorted or blurred vision [ 1 ]. Among patients undergoing cataract surgery, around 40% exhibit corneal astigmatism of 1.0 diopter …
verfasst von:
Soonwon Yang, Jaehyun Park, Woong Joo Whang, Yong-Soo Byun, Hyun Seung Kim, So-Hyang Chung
The application of immunotherapy in managing advanced metastatic melanoma has markedly improved patient outcomes [ 1 ]. Even though the incidence of melanoma continues to rise [ 1 ], the median survival time for patients with advanced, inoperable …
